Targeting Hypertension with the Peregrine System™ using dehydrated alcohol
Ablative Solutions is studying the use of the Peregrine System with dehydrated alcohol as a transcatheter alcohol-mediated renal denervation procedure with the goal of helping reduce blood pressure for people with hypertension that is not well controlled.
The alcohol-mediated renal denervation procedure is performed using the Peregrine System Kit, which is designed to deliver a neurolytic solution (alcohol) in the perivascular space of the renal artery to ablate the nerves known to influence the body’s regulation of blood pressure.
The TARGET BP I clinical trial (NCT02910414), assesses the efficacy and safety of renal denervation using the investigational Peregrine System Kit.
1 Williams et al, 2018 ESC/ESH Guidelines for the management of arterial hypertension, European Heart Journal (2018), 1–98 doi:10.1093/eurheartj/ehy339