Targeting Hypertension with the Peregrine System™ using dehydrated alcohol
Ablative Solutions is studying the use of the Peregrine System with dehydrated alcohol as a transcatheter alcohol-mediated renal denervation procedure with the goal of helping reduce blood pressure for people with hypertension that is not well controlled.
The alcohol-mediated renal denervation procedure is performed using the Peregrine System Kit, which is designed to deliver a neurolytic solution (alcohol) in the perivascular space of the renal artery to ablate the nerves known to influence the body’s regulation of blood pressure.
The TARGET BP Clinical Trial program is investigating the Peregrine System Kit, comprised of the Peregrine Catheter and dehydrated alcohol, to assess the efficacy and safety of this alcohol mediated procedure.
The TARGET BP I clinical trial (NCT02910414), assesses the efficacy and safety of renal denervation using the investigational Peregrine System Kit.
1 Williams et al, 2018 ESC/ESH Guidelines for the management of arterial hypertension, European Heart Journal (2018), 1–98 doi:10.1093/eurheartj/ehy339