Targeting Hypertension with the Peregrine System™ Kit

Ablative Solutions is studying the Peregrine System Kit as a transcatheter alcohol-mediated renal denervation procedure with the goal of helping reduce blood pressure for people with hypertension that is not well controlled.

The Peregrine Procedure is performed using the Peregrine System Kit, which is designed to deliver a neurolytic solution in the perivascular space of the renal artery to ablate the nerves known to influence the body’s regulation of blood pressure.

The TARGET BP I Clinical Trial program is currently investigating the Peregrine System Kit with the goal of helping patients with hypertension reduce their blood pressure despite taking anti-hypertension medications.

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The TARGET BP I clinical trial (NCT02910414), assesses the efficacy and safety of renal denervation using the investigational Peregrine System Kit.

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1 Williams et al, 2018 ESC/ESH Guidelines for the management of arterial hypertension, European Heart Journal (2018), 1–98  doi:10.1093/eurheartj/ehy339

2 CDC, https://www.cdc.gov/bloodpressure